Does GIVOSIRAN Cause Hepatic function abnormal? 6 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 6 reports of Hepatic function abnormal have been filed in association with GIVOSIRAN (GIVLAARI). This represents 0.5% of all adverse event reports for GIVOSIRAN.
6
Reports of Hepatic function abnormal with GIVOSIRAN
0.5%
of all GIVOSIRAN reports
0
Deaths
2
Hospitalizations
How Dangerous Is Hepatic function abnormal From GIVOSIRAN?
Of the 6 reports, 2 (33.3%) required hospitalization, and 1 (16.7%) were considered life-threatening.
Is Hepatic function abnormal Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for GIVOSIRAN. However, 6 reports have been filed with the FAERS database.
What Other Side Effects Does GIVOSIRAN Cause?
Porphyria acute (381)
Hospitalisation (141)
Nausea (91)
Product dose omission issue (85)
Fatigue (84)
Therapy interrupted (83)
Pain (74)
Intentional dose omission (63)
Abdominal pain (62)
Vomiting (58)
What Other Drugs Cause Hepatic function abnormal?
NIVOLUMAB (1,131)
PEMBROLIZUMAB (1,079)
METHOTREXATE (1,054)
CABOZANTINIB S-MALATE (912)
CYCLOPHOSPHAMIDE (824)
BEVACIZUMAB (769)
PACLITAXEL (603)
LENVATINIB (528)
ATORVASTATIN (520)
CYCLOSPORINE (508)
Which GIVOSIRAN Alternatives Have Lower Hepatic function abnormal Risk?
GIVOSIRAN vs GLASDEGIB
GIVOSIRAN vs GLATIRAMER
GIVOSIRAN vs GLECAPREVIR\PIBRENTASVIR
GIVOSIRAN vs GLEEVEC
GIVOSIRAN vs GLICLAZIDE