GLIVEC for Chronic myeloid leukaemia: Side Effects & Safety Data
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There are 636 adverse event reports in the FDA FAERS database where GLIVEC was used for Chronic myeloid leukaemia.
Most Reported Side Effects for GLIVEC
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Death | 628 | 63.1% | 628 | 14 |
| Malignant neoplasm progression | 60 | 6.0% | 53 | 12 |
| Gastrointestinal stromal tumour | 40 | 4.0% | 30 | 12 |
| Chronic myeloid leukaemia | 38 | 3.8% | 34 | 6 |
| Anaemia | 30 | 3.0% | 18 | 13 |
| Second primary malignancy | 27 | 2.7% | 5 | 12 |
| Pyrexia | 21 | 2.1% | 16 | 9 |
| Blast crisis in myelogenous leukaemia | 20 | 2.0% | 20 | 3 |
| Dyspnoea | 19 | 1.9% | 14 | 9 |
| Malaise | 16 | 1.6% | 7 | 6 |
| Thrombocytopenia | 16 | 1.6% | 10 | 5 |
| Vomiting | 16 | 1.6% | 9 | 11 |
| Diarrhoea | 15 | 1.5% | 6 | 8 |
| General physical health deterioration | 15 | 1.5% | 13 | 8 |
| Nausea | 15 | 1.5% | 10 | 8 |
Other Indications for GLIVEC
Gastrointestinal stromal tumour (231)
Acute lymphocytic leukaemia (61)
Gastrointestinal neoplasm (61)
Chromosome analysis abnormal (14)
Acute myeloid leukaemia (10)
Off label use (6)
Other Drugs Used for Chronic myeloid leukaemia
IMATINIB (18,795)
DASATINIB (15,612)
NILOTINIB (14,842)
PONATINIB (4,723)
BOSUTINIB (4,231)
ASCIMINIB (1,377)
TASIGNA (562)
OMACETAXINE MEPESUCCINATE (500)
HYDROXYUREA (457)
CYTARABINE (241)