Does GLUCARPIDASE Cause Pancytopenia? 6 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 6 reports of Pancytopenia have been filed in association with GLUCARPIDASE (Voraxaze). This represents 2.2% of all adverse event reports for GLUCARPIDASE.
6
Reports of Pancytopenia with GLUCARPIDASE
2.2%
of all GLUCARPIDASE reports
2
Deaths
1
Hospitalizations
How Dangerous Is Pancytopenia From GLUCARPIDASE?
Of the 6 reports, 2 (33.3%) resulted in death, 1 (16.7%) required hospitalization, and 1 (16.7%) were considered life-threatening.
Is Pancytopenia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for GLUCARPIDASE. However, 6 reports have been filed with the FAERS database.
What Other Side Effects Does GLUCARPIDASE Cause?
Off label use (83)
Underdose (61)
Laboratory test interference (57)
Drug effect incomplete (31)
Rebound effect (28)
Drug ineffective (27)
Blood creatinine increased (26)
Acute kidney injury (24)
Toxicity to various agents (24)
Renal failure (20)
What Other Drugs Cause Pancytopenia?
METHOTREXATE (5,377)
CYCLOPHOSPHAMIDE (3,351)
CARBOPLATIN (2,910)
RITUXIMAB (2,400)
LENALIDOMIDE (2,259)
DOXORUBICIN (2,212)
VINCRISTINE (2,180)
ETOPOSIDE (2,129)
DEXAMETHASONE (2,053)
PREDNISONE (1,743)
Which GLUCARPIDASE Alternatives Have Lower Pancytopenia Risk?
GLUCARPIDASE vs GLUCOPHAGE
GLUCARPIDASE vs GLUCOSAMINE
GLUCARPIDASE vs GLUTAMINE
GLUCARPIDASE vs GLUTATHIONE
GLUCARPIDASE vs GLYBURIDE