Does HYDROCHLOROTHIAZIDE Cause Lactic acidosis? 352 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 352 reports of Lactic acidosis have been filed in association with HYDROCHLOROTHIAZIDE (Irbesartan and Hydrochlorothiazide). This represents 1.7% of all adverse event reports for HYDROCHLOROTHIAZIDE.
352
Reports of Lactic acidosis with HYDROCHLOROTHIAZIDE
1.7%
of all HYDROCHLOROTHIAZIDE reports
47
Deaths
263
Hospitalizations
How Dangerous Is Lactic acidosis From HYDROCHLOROTHIAZIDE?
Of the 352 reports, 47 (13.4%) resulted in death, 263 (74.7%) required hospitalization, and 164 (46.6%) were considered life-threatening.
Is Lactic acidosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for HYDROCHLOROTHIAZIDE. However, 352 reports have been filed with the FAERS database.
What Other Side Effects Does HYDROCHLOROTHIAZIDE Cause?
Hyponatraemia (2,138)
Drug ineffective (1,889)
Acute kidney injury (1,838)
Nausea (1,536)
Dyspnoea (1,521)
Dizziness (1,469)
Headache (1,419)
Hypotension (1,347)
Fall (1,323)
Malaise (1,312)
What Other Drugs Cause Lactic acidosis?
METFORMIN (16,316)
AMLODIPINE (886)
LINEZOLID (824)
FUROSEMIDE (698)
ACETAMINOPHEN (561)
METFORMIN\SITAGLIPTIN (557)
ALBUTEROL (467)
EMPAGLIFLOZIN (434)
RAMIPRIL (430)
BISOPROLOL (425)
Which HYDROCHLOROTHIAZIDE Alternatives Have Lower Lactic acidosis Risk?
HYDROCHLOROTHIAZIDE vs HYDROCHLOROTHIAZIDE\IRBESARTAN
HYDROCHLOROTHIAZIDE vs HYDROCHLOROTHIAZIDE\LISINOPRIL
HYDROCHLOROTHIAZIDE vs HYDROCHLOROTHIAZIDE\LOSARTAN
HYDROCHLOROTHIAZIDE vs HYDROCHLOROTHIAZIDE\METOPROLOL
HYDROCHLOROTHIAZIDE vs HYDROCHLOROTHIAZIDE\NEBIVOLOL