Lactic acidosis: Which Medications Cause It? (23,801 Reports Across 728 Drugs)
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Lactic acidosis has been reported as an adverse event with 728 different drugs in the FDA's FAERS database, with 23,801 total reports. 4,854 of these reports resulted in death.The drugs most commonly associated with Lactic acidosis are METFORMIN, AMLODIPINE, and LINEZOLID.
23,801
Total Reports
728
Drugs Involved
4,854
Deaths
17,290
Hospitalizations
60.7 yrs
Average Patient Age
52.1% / 47.9%
Female / Male
Which Drugs Cause Lactic acidosis Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| METFORMIN | 16,316 | 17.9% | 2,912 | 11,967 | 6,100 |
| AMLODIPINE | 886 | 1.4% | 180 | 707 | 454 |
| LINEZOLID | 824 | 4.6% | 146 | 419 | 210 |
| FUROSEMIDE | 698 | 1.4% | 188 | 338 | 294 |
| ACETAMINOPHEN | 561 | 0.4% | 155 | 371 | 244 |
| METFORMIN\SITAGLIPTIN | 557 | 6.3% | 132 | 313 | 240 |
| ALBUTEROL | 467 | 0.5% | 26 | 285 | 52 |
| EMPAGLIFLOZIN | 434 | 1.2% | 61 | 309 | 143 |
| RAMIPRIL | 430 | 1.3% | 98 | 223 | 199 |
| BISOPROLOL | 425 | 1.5% | 172 | 145 | 223 |
| IBUPROFEN | 412 | 0.5% | 40 | 319 | 176 |
| GLICLAZIDE | 373 | 6.5% | 91 | 142 | 173 |
| HYDROCHLOROTHIAZIDE | 352 | 1.7% | 47 | 263 | 164 |
| ATORVASTATIN | 328 | 0.4% | 110 | 155 | 133 |
| DAPAGLIFLOZIN | 321 | 1.5% | 29 | 253 | 110 |
| ASPIRIN DL-LYSINE | 312 | 4.7% | 113 | 30 | 171 |
| VENLAFAXINE | 298 | 0.6% | 15 | 263 | 118 |
| SITAGLIPTIN | 289 | 1.5% | 55 | 171 | 96 |
| METFORMIN\VILDAGLIPTIN | 279 | 9.7% | 33 | 171 | 173 |
| ASPIRIN | 278 | 0.3% | 78 | 199 | 99 |