Does HYDROCHLOROTHIAZIDE Cause Left ventricular dysfunction? 42 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 42 reports of Left ventricular dysfunction have been filed in association with HYDROCHLOROTHIAZIDE (Irbesartan and Hydrochlorothiazide). This represents 0.2% of all adverse event reports for HYDROCHLOROTHIAZIDE.
42
Reports of Left ventricular dysfunction with HYDROCHLOROTHIAZIDE
0.2%
of all HYDROCHLOROTHIAZIDE reports
1
Deaths
38
Hospitalizations
How Dangerous Is Left ventricular dysfunction From HYDROCHLOROTHIAZIDE?
Of the 42 reports, 1 (2.4%) resulted in death, 38 (90.5%) required hospitalization, and 2 (4.8%) were considered life-threatening.
Is Left ventricular dysfunction Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for HYDROCHLOROTHIAZIDE. However, 42 reports have been filed with the FAERS database.
What Other Side Effects Does HYDROCHLOROTHIAZIDE Cause?
Hyponatraemia (2,138)
Drug ineffective (1,889)
Acute kidney injury (1,838)
Nausea (1,536)
Dyspnoea (1,521)
Dizziness (1,469)
Headache (1,419)
Hypotension (1,347)
Fall (1,323)
Malaise (1,312)
What Other Drugs Cause Left ventricular dysfunction?
DOXORUBICIN (430)
CYCLOPHOSPHAMIDE (426)
TRASTUZUMAB (401)
CLOZAPINE (231)
SACUBITRIL\VALSARTAN (231)
BISOPROLOL (225)
PERTUZUMAB (207)
RITUXIMAB (202)
DOCETAXEL (199)
VINCRISTINE (193)
Which HYDROCHLOROTHIAZIDE Alternatives Have Lower Left ventricular dysfunction Risk?
HYDROCHLOROTHIAZIDE vs HYDROCHLOROTHIAZIDE\IRBESARTAN
HYDROCHLOROTHIAZIDE vs HYDROCHLOROTHIAZIDE\LISINOPRIL
HYDROCHLOROTHIAZIDE vs HYDROCHLOROTHIAZIDE\LOSARTAN
HYDROCHLOROTHIAZIDE vs HYDROCHLOROTHIAZIDE\METOPROLOL
HYDROCHLOROTHIAZIDE vs HYDROCHLOROTHIAZIDE\NEBIVOLOL