Left ventricular dysfunction: Which Medications Cause It? (4,610 Reports Across 434 Drugs)
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Left ventricular dysfunction has been reported as an adverse event with 434 different drugs in the FDA's FAERS database, with 4,610 total reports. 535 of these reports resulted in death.The drugs most commonly associated with Left ventricular dysfunction are DOXORUBICIN, CYCLOPHOSPHAMIDE, and TRASTUZUMAB.
4,610
Total Reports
434
Drugs Involved
535
Deaths
2,732
Hospitalizations
54.5 yrs
Average Patient Age
52.6% / 47.4%
Female / Male
Which Drugs Cause Left ventricular dysfunction Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| DOXORUBICIN | 430 | 0.5% | 73 | 182 | 81 |
| CYCLOPHOSPHAMIDE | 426 | 0.3% | 74 | 186 | 65 |
| TRASTUZUMAB | 401 | 0.9% | 51 | 165 | 31 |
| CLOZAPINE | 231 | 0.2% | 3 | 112 | 24 |
| SACUBITRIL\VALSARTAN | 231 | 0.2% | 18 | 138 | 11 |
| BISOPROLOL | 225 | 0.8% | 2 | 155 | 5 |
| PERTUZUMAB | 207 | 0.9% | 24 | 88 | 14 |
| RITUXIMAB | 202 | 0.1% | 16 | 73 | 17 |
| DOCETAXEL | 199 | 0.3% | 46 | 117 | 21 |
| VINCRISTINE | 193 | 0.3% | 23 | 74 | 31 |
| PACLITAXEL | 185 | 0.2% | 35 | 88 | 12 |
| ASPIRIN | 179 | 0.2% | 9 | 139 | 11 |
| FUROSEMIDE | 177 | 0.3% | 7 | 120 | 17 |
| PREDNISONE | 174 | 0.1% | 13 | 70 | 40 |
| METHOTREXATE | 163 | 0.1% | 17 | 75 | 15 |
| FLUOROURACIL | 149 | 0.3% | 14 | 95 | 36 |
| CARBOPLATIN | 140 | 0.2% | 21 | 85 | 19 |
| METOPROLOL | 140 | 0.3% | 4 | 114 | 15 |
| AMIODARONE | 127 | 0.5% | 9 | 90 | 12 |
| AMLODIPINE | 125 | 0.2% | 6 | 113 | 31 |