Does PACLITAXEL Cause Left ventricular dysfunction? 185 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 185 reports of Left ventricular dysfunction have been filed in association with PACLITAXEL (PACLITAXEL PACLITAXEL). This represents 0.2% of all adverse event reports for PACLITAXEL.
185
Reports of Left ventricular dysfunction with PACLITAXEL
0.2%
of all PACLITAXEL reports
35
Deaths
88
Hospitalizations
How Dangerous Is Left ventricular dysfunction From PACLITAXEL?
Of the 185 reports, 35 (18.9%) resulted in death, 88 (47.6%) required hospitalization, and 12 (6.5%) were considered life-threatening.
Is Left ventricular dysfunction Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PACLITAXEL. However, 185 reports have been filed with the FAERS database.
What Other Side Effects Does PACLITAXEL Cause?
Neutropenia (4,553)
Nausea (4,521)
Dyspnoea (4,519)
Diarrhoea (4,289)
Off label use (4,075)
Anaemia (3,949)
Neuropathy peripheral (3,508)
Malignant neoplasm progression (3,484)
Fatigue (3,418)
Death (3,143)
What Other Drugs Cause Left ventricular dysfunction?
DOXORUBICIN (430)
CYCLOPHOSPHAMIDE (426)
TRASTUZUMAB (401)
CLOZAPINE (231)
SACUBITRIL\VALSARTAN (231)
BISOPROLOL (225)
PERTUZUMAB (207)
RITUXIMAB (202)
DOCETAXEL (199)
VINCRISTINE (193)
Which PACLITAXEL Alternatives Have Lower Left ventricular dysfunction Risk?
PACLITAXEL vs PACRITINIB
PACLITAXEL vs PALBOCICLIB
PACLITAXEL vs PALIPERIDONE
PACLITAXEL vs PALIVIZUMAB
PACLITAXEL vs PALONOSETRON