Does HYDROCHLOROTHIAZIDE Cause Metabolic acidosis? 134 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 134 reports of Metabolic acidosis have been filed in association with HYDROCHLOROTHIAZIDE (Irbesartan and Hydrochlorothiazide). This represents 0.6% of all adverse event reports for HYDROCHLOROTHIAZIDE.
134
Reports of Metabolic acidosis with HYDROCHLOROTHIAZIDE
0.6%
of all HYDROCHLOROTHIAZIDE reports
25
Deaths
109
Hospitalizations
How Dangerous Is Metabolic acidosis From HYDROCHLOROTHIAZIDE?
Of the 134 reports, 25 (18.7%) resulted in death, 109 (81.3%) required hospitalization, and 39 (29.1%) were considered life-threatening.
Is Metabolic acidosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for HYDROCHLOROTHIAZIDE. However, 134 reports have been filed with the FAERS database.
What Other Side Effects Does HYDROCHLOROTHIAZIDE Cause?
Hyponatraemia (2,138)
Drug ineffective (1,889)
Acute kidney injury (1,838)
Nausea (1,536)
Dyspnoea (1,521)
Dizziness (1,469)
Headache (1,419)
Hypotension (1,347)
Fall (1,323)
Malaise (1,312)
What Other Drugs Cause Metabolic acidosis?
METFORMIN (5,236)
ACETAMINOPHEN (2,538)
AMLODIPINE (1,202)
IBUPROFEN (974)
EMPAGLIFLOZIN (572)
TACROLIMUS (491)
VENLAFAXINE (460)
FLUOXETINE (437)
ESOMEPRAZOLE (430)
FUROSEMIDE (413)
Which HYDROCHLOROTHIAZIDE Alternatives Have Lower Metabolic acidosis Risk?
HYDROCHLOROTHIAZIDE vs HYDROCHLOROTHIAZIDE\IRBESARTAN
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HYDROCHLOROTHIAZIDE vs HYDROCHLOROTHIAZIDE\METOPROLOL
HYDROCHLOROTHIAZIDE vs HYDROCHLOROTHIAZIDE\NEBIVOLOL