Metabolic acidosis: Which Medications Cause It? (22,464 Reports Across 874 Drugs)
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Metabolic acidosis has been reported as an adverse event with 874 different drugs in the FDA's FAERS database, with 22,464 total reports. 5,626 of these reports resulted in death.The drugs most commonly associated with Metabolic acidosis are METFORMIN, ACETAMINOPHEN, and AMLODIPINE.
22,464
Total Reports
874
Drugs Involved
5,626
Deaths
16,740
Hospitalizations
52.8 yrs
Average Patient Age
53.3% / 46.7%
Female / Male
Which Drugs Cause Metabolic acidosis Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| METFORMIN | 5,236 | 5.8% | 910 | 4,132 | 1,724 |
| ACETAMINOPHEN | 2,538 | 1.9% | 815 | 1,618 | 609 |
| AMLODIPINE | 1,202 | 1.9% | 258 | 889 | 494 |
| IBUPROFEN | 974 | 1.1% | 124 | 816 | 410 |
| EMPAGLIFLOZIN | 572 | 1.5% | 75 | 449 | 167 |
| TACROLIMUS | 491 | 0.5% | 96 | 382 | 117 |
| VENLAFAXINE | 460 | 1.0% | 54 | 227 | 153 |
| FLUOXETINE | 437 | 1.4% | 94 | 186 | 124 |
| ESOMEPRAZOLE | 430 | 0.6% | 42 | 134 | 86 |
| FUROSEMIDE | 413 | 0.8% | 34 | 326 | 112 |
| DAPAGLIFLOZIN | 408 | 1.9% | 19 | 330 | 119 |
| TRAMADOL | 393 | 0.5% | 50 | 196 | 101 |
| QUETIAPINE | 385 | 0.5% | 164 | 239 | 130 |
| TOPIRAMATE | 385 | 1.4% | 68 | 236 | 80 |
| CANAGLIFLOZIN | 353 | 1.5% | 11 | 313 | 51 |
| METOPROLOL | 295 | 0.7% | 117 | 210 | 88 |
| SPIRONOLACTONE | 290 | 1.4% | 24 | 231 | 66 |
| ESCITALOPRAM OXALATE | 289 | 1.0% | 29 | 83 | 88 |
| PREDNISONE | 285 | 0.2% | 95 | 245 | 99 |
| ASPIRIN | 283 | 0.3% | 33 | 218 | 88 |