Does HYDROCHLOROTHIAZIDE Cause Nephrocalcinosis? 18 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 18 reports of Nephrocalcinosis have been filed in association with HYDROCHLOROTHIAZIDE (Irbesartan and Hydrochlorothiazide). This represents 0.1% of all adverse event reports for HYDROCHLOROTHIAZIDE.
18
Reports of Nephrocalcinosis with HYDROCHLOROTHIAZIDE
0.1%
of all HYDROCHLOROTHIAZIDE reports
11
Deaths
16
Hospitalizations
How Dangerous Is Nephrocalcinosis From HYDROCHLOROTHIAZIDE?
Of the 18 reports, 11 (61.1%) resulted in death, 16 (88.9%) required hospitalization, and 14 (77.8%) were considered life-threatening.
Is Nephrocalcinosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for HYDROCHLOROTHIAZIDE. However, 18 reports have been filed with the FAERS database.
What Other Side Effects Does HYDROCHLOROTHIAZIDE Cause?
Hyponatraemia (2,138)
Drug ineffective (1,889)
Acute kidney injury (1,838)
Nausea (1,536)
Dyspnoea (1,521)
Dizziness (1,469)
Headache (1,419)
Hypotension (1,347)
Fall (1,323)
Malaise (1,312)
What Other Drugs Cause Nephrocalcinosis?
FUROSEMIDE (111)
CALCIUM (65)
CALCITRIOL (64)
LANSOPRAZOLE (51)
OMEPRAZOLE (49)
ASFOTASE ALFA (45)
PANTOPRAZOLE (41)
PREDNISOLONE (39)
SODIUM, DIBASIC\SODIUM, MONOBASIC (32)
DENOSUMAB (31)
Which HYDROCHLOROTHIAZIDE Alternatives Have Lower Nephrocalcinosis Risk?
HYDROCHLOROTHIAZIDE vs HYDROCHLOROTHIAZIDE\IRBESARTAN
HYDROCHLOROTHIAZIDE vs HYDROCHLOROTHIAZIDE\LISINOPRIL
HYDROCHLOROTHIAZIDE vs HYDROCHLOROTHIAZIDE\LOSARTAN
HYDROCHLOROTHIAZIDE vs HYDROCHLOROTHIAZIDE\METOPROLOL
HYDROCHLOROTHIAZIDE vs HYDROCHLOROTHIAZIDE\NEBIVOLOL