Nephrocalcinosis: Which Medications Cause It? (820 Reports Across 90 Drugs)
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Nephrocalcinosis has been reported as an adverse event with 90 different drugs in the FDA's FAERS database, with 820 total reports. 39 of these reports resulted in death.The drugs most commonly associated with Nephrocalcinosis are FUROSEMIDE, CALCIUM, and CALCITRIOL.
820
Total Reports
90
Drugs Involved
39
Deaths
338
Hospitalizations
36.9 yrs
Average Patient Age
58.4% / 41.6%
Female / Male
Which Drugs Cause Nephrocalcinosis Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| FUROSEMIDE | 111 | 0.2% | 11 | 61 | 12 |
| CALCIUM | 65 | 0.4% | 0 | 31 | 1 |
| CALCITRIOL | 64 | 2.7% | 0 | 23 | 1 |
| LANSOPRAZOLE | 51 | 0.1% | 10 | 6 | 3 |
| OMEPRAZOLE | 49 | 0.1% | 8 | 5 | 2 |
| ASFOTASE ALFA | 45 | 0.5% | 0 | 10 | 1 |
| PANTOPRAZOLE | 41 | 0.1% | 4 | 18 | 2 |
| PREDNISOLONE | 39 | 0.1% | 1 | 16 | 0 |
| SODIUM, DIBASIC\SODIUM, MONOBASIC | 32 | 9.2% | 0 | 19 | 0 |
| DENOSUMAB | 31 | 0.0% | 3 | 17 | 2 |
| CINACALCET | 30 | 0.1% | 5 | 5 | 0 |
| ESOMEPRAZOLE | 28 | 0.0% | 5 | 5 | 5 |
| CHOLECALCIFEROL | 27 | 0.2% | 0 | 16 | 1 |
| SPIRONOLACTONE | 24 | 0.1% | 11 | 22 | 9 |
| TOPIRAMATE | 24 | 0.1% | 0 | 5 | 1 |
| ALLOPURINOL | 22 | 0.1% | 0 | 21 | 0 |
| BUROSUMAB-TWZA | 21 | 0.4% | 0 | 0 | 0 |
| ERGOCALCIFEROL | 21 | 0.4% | 0 | 17 | 0 |
| IBUPROFEN | 20 | 0.0% | 0 | 15 | 1 |
| HYDROCHLOROTHIAZIDE | 18 | 0.1% | 11 | 16 | 14 |