Does SPIRONOLACTONE Cause Nephrocalcinosis? 24 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 24 reports of Nephrocalcinosis have been filed in association with SPIRONOLACTONE (spironolactone). This represents 0.1% of all adverse event reports for SPIRONOLACTONE.
24
Reports of Nephrocalcinosis with SPIRONOLACTONE
0.1%
of all SPIRONOLACTONE reports
11
Deaths
22
Hospitalizations
How Dangerous Is Nephrocalcinosis From SPIRONOLACTONE?
Of the 24 reports, 11 (45.8%) resulted in death, 22 (91.7%) required hospitalization, and 9 (37.5%) were considered life-threatening.
Is Nephrocalcinosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for SPIRONOLACTONE. However, 24 reports have been filed with the FAERS database.
What Other Side Effects Does SPIRONOLACTONE Cause?
Acute kidney injury (3,273)
Hyperkalaemia (2,518)
Hypotension (1,583)
Dyspnoea (1,468)
Drug ineffective (1,379)
Hyponatraemia (1,166)
Dizziness (991)
Fatigue (990)
Fall (947)
Off label use (899)
What Other Drugs Cause Nephrocalcinosis?
FUROSEMIDE (111)
CALCIUM (65)
CALCITRIOL (64)
LANSOPRAZOLE (51)
OMEPRAZOLE (49)
ASFOTASE ALFA (45)
PANTOPRAZOLE (41)
PREDNISOLONE (39)
SODIUM, DIBASIC\SODIUM, MONOBASIC (32)
DENOSUMAB (31)
Which SPIRONOLACTONE Alternatives Have Lower Nephrocalcinosis Risk?
SPIRONOLACTONE vs SPRYCEL
SPIRONOLACTONE vs STALEVO
SPIRONOLACTONE vs STANNOUS FLUORIDE
SPIRONOLACTONE vs STANOZOLOL
SPIRONOLACTONE vs STAVUDINE