Does HYDROCHLOROTHIAZIDE Cause Patent ductus arteriosus? 27 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 27 reports of Patent ductus arteriosus have been filed in association with HYDROCHLOROTHIAZIDE (Irbesartan and Hydrochlorothiazide). This represents 0.1% of all adverse event reports for HYDROCHLOROTHIAZIDE.
27
Reports of Patent ductus arteriosus with HYDROCHLOROTHIAZIDE
0.1%
of all HYDROCHLOROTHIAZIDE reports
10
Deaths
4
Hospitalizations
How Dangerous Is Patent ductus arteriosus From HYDROCHLOROTHIAZIDE?
Of the 27 reports, 10 (37.0%) resulted in death, 4 (14.8%) required hospitalization, and 4 (14.8%) were considered life-threatening.
Is Patent ductus arteriosus Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for HYDROCHLOROTHIAZIDE. However, 27 reports have been filed with the FAERS database.
What Other Side Effects Does HYDROCHLOROTHIAZIDE Cause?
Hyponatraemia (2,138)
Drug ineffective (1,889)
Acute kidney injury (1,838)
Nausea (1,536)
Dyspnoea (1,521)
Dizziness (1,469)
Headache (1,419)
Hypotension (1,347)
Fall (1,323)
Malaise (1,312)
What Other Drugs Cause Patent ductus arteriosus?
ONDANSETRON (185)
LAMOTRIGINE (168)
PAROXETINE (168)
ACETAMINOPHEN (154)
VENLAFAXINE (135)
SERTRALINE (130)
LEVETIRACETAM (122)
FLUOXETINE (107)
METOPROLOL (104)
RAMIPRIL (98)
Which HYDROCHLOROTHIAZIDE Alternatives Have Lower Patent ductus arteriosus Risk?
HYDROCHLOROTHIAZIDE vs HYDROCHLOROTHIAZIDE\IRBESARTAN
HYDROCHLOROTHIAZIDE vs HYDROCHLOROTHIAZIDE\LISINOPRIL
HYDROCHLOROTHIAZIDE vs HYDROCHLOROTHIAZIDE\LOSARTAN
HYDROCHLOROTHIAZIDE vs HYDROCHLOROTHIAZIDE\METOPROLOL
HYDROCHLOROTHIAZIDE vs HYDROCHLOROTHIAZIDE\NEBIVOLOL