Patent ductus arteriosus: Which Medications Cause It? (2,367 Reports Across 237 Drugs)
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Patent ductus arteriosus has been reported as an adverse event with 237 different drugs in the FDA's FAERS database, with 2,367 total reports. 187 of these reports resulted in death.The drugs most commonly associated with Patent ductus arteriosus are ONDANSETRON, LAMOTRIGINE, and PAROXETINE.
2,367
Total Reports
237
Drugs Involved
187
Deaths
646
Hospitalizations
15.2 yrs
Average Patient Age
54.3% / 45.7%
Female / Male
Which Drugs Cause Patent ductus arteriosus Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| ONDANSETRON | 185 | 0.8% | 23 | 41 | 16 |
| LAMOTRIGINE | 168 | 0.4% | 2 | 42 | 2 |
| PAROXETINE | 168 | 0.8% | 8 | 70 | 4 |
| ACETAMINOPHEN | 154 | 0.1% | 1 | 29 | 4 |
| VENLAFAXINE | 135 | 0.3% | 9 | 44 | 19 |
| SERTRALINE | 130 | 0.2% | 11 | 39 | 17 |
| LEVETIRACETAM | 122 | 0.2% | 0 | 35 | 1 |
| FLUOXETINE | 107 | 0.3% | 12 | 43 | 47 |
| METOPROLOL | 104 | 0.3% | 3 | 20 | 5 |
| RAMIPRIL | 98 | 0.3% | 8 | 13 | 2 |
| IBUPROFEN | 95 | 0.1% | 13 | 26 | 22 |
| QUETIAPINE | 84 | 0.1% | 8 | 22 | 14 |
| METHYLDOPA | 65 | 2.5% | 2 | 5 | 4 |
| VALPROIC ACID | 56 | 0.3% | 2 | 24 | 3 |
| PREDNISOLONE | 55 | 0.1% | 3 | 8 | 3 |
| VALSARTAN | 54 | 0.3% | 1 | 15 | 9 |
| BETAMETHASONE | 52 | 0.7% | 1 | 13 | 0 |
| CEFUROXIME | 51 | 1.0% | 1 | 2 | 0 |
| ASPIRIN | 50 | 0.1% | 2 | 16 | 1 |
| METFORMIN | 48 | 0.1% | 3 | 9 | 3 |