Does HYDROCHLOROTHIAZIDE Cause Pneumothorax? 14 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 14 reports of Pneumothorax have been filed in association with HYDROCHLOROTHIAZIDE (Irbesartan and Hydrochlorothiazide). This represents 0.1% of all adverse event reports for HYDROCHLOROTHIAZIDE.
14
Reports of Pneumothorax with HYDROCHLOROTHIAZIDE
0.1%
of all HYDROCHLOROTHIAZIDE reports
3
Deaths
3
Hospitalizations
How Dangerous Is Pneumothorax From HYDROCHLOROTHIAZIDE?
Of the 14 reports, 3 (21.4%) resulted in death, 3 (21.4%) required hospitalization, and 3 (21.4%) were considered life-threatening.
Is Pneumothorax Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for HYDROCHLOROTHIAZIDE. However, 14 reports have been filed with the FAERS database.
What Other Side Effects Does HYDROCHLOROTHIAZIDE Cause?
Hyponatraemia (2,138)
Drug ineffective (1,889)
Acute kidney injury (1,838)
Nausea (1,536)
Dyspnoea (1,521)
Dizziness (1,469)
Headache (1,419)
Hypotension (1,347)
Fall (1,323)
Malaise (1,312)
What Other Drugs Cause Pneumothorax?
ADALIMUMAB (530)
METHOTREXATE (380)
NINTEDANIB (310)
BEVACIZUMAB (293)
PREDNISONE (283)
ALBUTEROL (278)
PACLITAXEL (267)
PEMBROLIZUMAB (258)
NIVOLUMAB (254)
CARBOPLATIN (234)
Which HYDROCHLOROTHIAZIDE Alternatives Have Lower Pneumothorax Risk?
HYDROCHLOROTHIAZIDE vs HYDROCHLOROTHIAZIDE\IRBESARTAN
HYDROCHLOROTHIAZIDE vs HYDROCHLOROTHIAZIDE\LISINOPRIL
HYDROCHLOROTHIAZIDE vs HYDROCHLOROTHIAZIDE\LOSARTAN
HYDROCHLOROTHIAZIDE vs HYDROCHLOROTHIAZIDE\METOPROLOL
HYDROCHLOROTHIAZIDE vs HYDROCHLOROTHIAZIDE\NEBIVOLOL