HYDROMORPHONE for Breakthrough pain: Side Effects & Safety Data

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There are 223 adverse event reports in the FDA FAERS database where HYDROMORPHONE was used for Breakthrough pain.

Most Reported Side Effects for HYDROMORPHONE

Side Effect	Reports	%	Deaths	Hosp.
Drug dependence	39,714	47.6%	4,428	2,454
Overdose	25,322	30.4%	9,229	1,528
Pain	21,325	25.6%	744	1,542
Emotional distress	18,260	21.9%	393	376
Death	15,276	18.3%	15,263	594
Drug withdrawal syndrome	14,834	17.8%	679	676
Toxicity to various agents	10,769	12.9%	9,077	1,752
Drug abuse	3,999	4.8%	1,982	909
Drug ineffective	3,562	4.3%	367	1,194
Drug withdrawal syndrome neonatal	3,333	4.0%	57	478
Anxiety	3,059	3.7%	257	604
Depression	2,742	3.3%	394	652
Nausea	2,683	3.2%	619	1,067
Off label use	2,633	3.2%	604	1,099
Drug hypersensitivity	2,588	3.1%	375	389