IBRUTINIB for B-cell lymphoma: Side Effects & Safety Data
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There are 933 adverse event reports in the FDA FAERS database where IBRUTINIB was used for B-cell lymphoma.
Most Reported Side Effects for IBRUTINIB
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Death | 8,007 | 10.7% | 7,998 | 836 |
| Off label use | 5,446 | 7.3% | 866 | 1,760 |
| Fatigue | 4,479 | 6.0% | 203 | 1,352 |
| Diarrhoea | 3,903 | 5.2% | 331 | 1,322 |
| Atrial fibrillation | 3,671 | 4.9% | 407 | 1,633 |
| Pneumonia | 3,015 | 4.0% | 679 | 2,279 |
| Incorrect dose administered | 2,752 | 3.7% | 250 | 887 |
| Contusion | 2,712 | 3.6% | 102 | 770 |
| Fall | 2,375 | 3.2% | 243 | 1,444 |
| Asthenia | 2,200 | 2.9% | 191 | 1,104 |
| Nausea | 2,142 | 2.9% | 146 | 764 |
| Arthralgia | 2,095 | 2.8% | 99 | 503 |
| Rash | 2,029 | 2.7% | 93 | 487 |
| Haemorrhage | 1,907 | 2.5% | 183 | 461 |
| Disease progression | 1,813 | 2.4% | 676 | 584 |
Other Indications for IBRUTINIB
Chronic lymphocytic leukaemia (37,003)
Product used for unknown indication (15,132)
Mantle cell lymphoma (6,306)
Waldenstrom's macroglobulinaemia (5,044)
B-cell small lymphocytic lymphoma (1,882)
Non-hodgkin's lymphoma (1,581)
Diffuse large b-cell lymphoma (1,382)
Lymphocytic leukaemia (1,308)
Lymphoma (896)
Marginal zone lymphoma (519)
Other Drugs Used for B-cell lymphoma
RITUXIMAB (7,811)
CYCLOPHOSPHAMIDE (4,766)
VINCRISTINE (4,346)
DOXORUBICIN (3,947)
LENALIDOMIDE (3,474)
PREDNISONE (2,561)
BENDAMUSTINE (1,668)
PREDNISOLONE (1,489)
ETOPOSIDE (1,268)
IDELALISIB (1,240)