IBRUTINIB for Mantle cell lymphoma: Side Effects & Safety Data
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There are 6,306 adverse event reports in the FDA FAERS database where IBRUTINIB was used for Mantle cell lymphoma.
Most Reported Side Effects for IBRUTINIB
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Death | 8,007 | 10.7% | 7,998 | 836 |
| Off label use | 5,446 | 7.3% | 866 | 1,760 |
| Fatigue | 4,479 | 6.0% | 203 | 1,352 |
| Diarrhoea | 3,903 | 5.2% | 331 | 1,322 |
| Atrial fibrillation | 3,671 | 4.9% | 407 | 1,633 |
| Pneumonia | 3,015 | 4.0% | 679 | 2,279 |
| Incorrect dose administered | 2,752 | 3.7% | 250 | 887 |
| Contusion | 2,712 | 3.6% | 102 | 770 |
| Fall | 2,375 | 3.2% | 243 | 1,444 |
| Asthenia | 2,200 | 2.9% | 191 | 1,104 |
| Nausea | 2,142 | 2.9% | 146 | 764 |
| Arthralgia | 2,095 | 2.8% | 99 | 503 |
| Rash | 2,029 | 2.7% | 93 | 487 |
| Haemorrhage | 1,907 | 2.5% | 183 | 461 |
| Disease progression | 1,813 | 2.4% | 676 | 584 |
Other Indications for IBRUTINIB
Chronic lymphocytic leukaemia (37,003)
Product used for unknown indication (15,132)
Waldenstrom's macroglobulinaemia (5,044)
B-cell small lymphocytic lymphoma (1,882)
Non-hodgkin's lymphoma (1,581)
Diffuse large b-cell lymphoma (1,382)
Lymphocytic leukaemia (1,308)
B-cell lymphoma (933)
Lymphoma (896)
Marginal zone lymphoma (519)
Other Drugs Used for Mantle cell lymphoma
RITUXIMAB (3,940)
LENALIDOMIDE (2,989)
CYCLOPHOSPHAMIDE (1,815)
DOXORUBICIN (1,396)
VENETOCLAX (1,367)
VINCRISTINE (1,361)
BENDAMUSTINE (1,227)
CYTARABINE (1,174)
DEXAMETHASONE (949)
PREDNISONE (852)