Does IBRUTINIB Cause Arthropathy? 185 Reports in FDA Database

Q: Does IBRUTINIB cause Arthropathy?

185 reports of Arthropathy have been filed with the FDA for IBRUTINIB, representing 0.3% of all IBRUTINIB adverse event reports.

Q: How dangerous is Arthropathy from IBRUTINIB?

Of 185 reports, 4 (2.2%) resulted in death and 65 required hospitalization.

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According to the FDA Adverse Event Reporting System (FAERS), 185 reports of Arthropathy have been filed in association with IBRUTINIB (Imbruvica). This represents 0.3% of all adverse event reports for IBRUTINIB.

185

Reports of Arthropathy with IBRUTINIB

0.3%

of all IBRUTINIB reports

Deaths

Hospitalizations

How Dangerous Is Arthropathy From IBRUTINIB?

Of the 185 reports, 4 (2.2%) resulted in death, 65 (35.1%) required hospitalization, and 1 (0.5%) were considered life-threatening.

Is Arthropathy Listed in the Official Label?

This adverse event is not currently listed in the official FDA drug label for IBRUTINIB. However, 185 reports have been filed with the FAERS database.

What Other Side Effects Does IBRUTINIB Cause?

Death (8,007) Off label use (5,446) Fatigue (4,479) Diarrhoea (3,903) Atrial fibrillation (3,671) Pneumonia (3,015) Incorrect dose administered (2,752) Contusion (2,712) Fall (2,375) Asthenia (2,200)

What Other Drugs Cause Arthropathy?

ETANERCEPT (11,842) ADALIMUMAB (11,670) ABATACEPT (11,099) METHOTREXATE (10,973) TOCILIZUMAB (9,816) LEFLUNOMIDE (9,277) HYDROXYCHLOROQUINE (8,770) RITUXIMAB (8,619) INFLIXIMAB (8,410) SULFASALAZINE (7,545)

Which IBRUTINIB Alternatives Have Lower Arthropathy Risk?

IBRUTINIB vs IBUPROFEN IBRUTINIB vs IBUPROFEN LYSINE IBRUTINIB vs IBUPROFEN UNKNOWN PRODUCT IBRUTINIB vs IBUPROFEN\IBUPROFEN IBRUTINIB vs IBUPROFEN\PHENYLEPHRINE

IBRUTINIB Full Profile All Arthropathy Reports All Drugs Causing Arthropathy IBRUTINIB Demographics