Does IBRUTINIB Cause Cardiac failure? 546 Reports in FDA Database

Q: Does IBRUTINIB cause Cardiac failure?

546 reports of Cardiac failure have been filed with the FDA for IBRUTINIB, representing 0.7% of all IBRUTINIB adverse event reports.

Q: How dangerous is Cardiac failure from IBRUTINIB?

Of 546 reports, 164 (30.0%) resulted in death and 314 required hospitalization.

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According to the FDA Adverse Event Reporting System (FAERS), 546 reports of Cardiac failure have been filed in association with IBRUTINIB (Imbruvica). This represents 0.7% of all adverse event reports for IBRUTINIB.

546

Reports of Cardiac failure with IBRUTINIB

0.7%

of all IBRUTINIB reports

164

Deaths

314

Hospitalizations

How Dangerous Is Cardiac failure From IBRUTINIB?

Of the 546 reports, 164 (30.0%) resulted in death, 314 (57.5%) required hospitalization, and 40 (7.3%) were considered life-threatening.

Is Cardiac failure Listed in the Official Label?

Yes, Cardiac failure is listed as a known adverse reaction in the official FDA drug label for IBRUTINIB.

What Other Side Effects Does IBRUTINIB Cause?

Death (8,007) Off label use (5,446) Fatigue (4,479) Diarrhoea (3,903) Atrial fibrillation (3,671) Pneumonia (3,015) Incorrect dose administered (2,752) Contusion (2,712) Fall (2,375) Asthenia (2,200)

What Other Drugs Cause Cardiac failure?

SACUBITRIL\VALSARTAN (4,504) FUROSEMIDE (1,841) APIXABAN (1,575) CYCLOPHOSPHAMIDE (1,514) DOXORUBICIN (1,367) ADALIMUMAB (1,278) DEXAMETHASONE (1,271) TREPROSTINIL (1,168) BISOPROLOL (1,159) LENALIDOMIDE (1,115)

Which IBRUTINIB Alternatives Have Lower Cardiac failure Risk?

IBRUTINIB vs IBUPROFEN IBRUTINIB vs IBUPROFEN LYSINE IBRUTINIB vs IBUPROFEN UNKNOWN PRODUCT IBRUTINIB vs IBUPROFEN\IBUPROFEN IBRUTINIB vs IBUPROFEN\PHENYLEPHRINE

IBRUTINIB Full Profile All Cardiac failure Reports All Drugs Causing Cardiac failure IBRUTINIB Demographics