Does IBRUTINIB Cause Deafness? 192 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 192 reports of Deafness have been filed in association with IBRUTINIB (Imbruvica). This represents 0.3% of all adverse event reports for IBRUTINIB.
192
Reports of Deafness with IBRUTINIB
0.3%
of all IBRUTINIB reports
3
Deaths
32
Hospitalizations
How Dangerous Is Deafness From IBRUTINIB?
Of the 192 reports, 3 (1.6%) resulted in death, 32 (16.7%) required hospitalization, and 1 (0.5%) were considered life-threatening.
Is Deafness Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for IBRUTINIB. However, 192 reports have been filed with the FAERS database.
What Other Side Effects Does IBRUTINIB Cause?
Death (8,007)
Off label use (5,446)
Fatigue (4,479)
Diarrhoea (3,903)
Atrial fibrillation (3,671)
Pneumonia (3,015)
Incorrect dose administered (2,752)
Contusion (2,712)
Fall (2,375)
Asthenia (2,200)
What Other Drugs Cause Deafness?
ADALIMUMAB (1,300)
METHOTREXATE (635)
ETANERCEPT (629)
SACUBITRIL\VALSARTAN (471)
APIXABAN (455)
LENALIDOMIDE (397)
TOFACITINIB (388)
CISPLATIN (344)
AMIKACIN (320)
ATORVASTATIN (308)
Which IBRUTINIB Alternatives Have Lower Deafness Risk?
IBRUTINIB vs IBUPROFEN
IBRUTINIB vs IBUPROFEN LYSINE
IBRUTINIB vs IBUPROFEN UNKNOWN PRODUCT
IBRUTINIB vs IBUPROFEN\IBUPROFEN
IBRUTINIB vs IBUPROFEN\PHENYLEPHRINE