Does METHOTREXATE Cause Deafness? 635 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 635 reports of Deafness have been filed in association with METHOTREXATE (Methotrexate). This represents 0.3% of all adverse event reports for METHOTREXATE.
635
Reports of Deafness with METHOTREXATE
0.3%
of all METHOTREXATE reports
1
Deaths
267
Hospitalizations
How Dangerous Is Deafness From METHOTREXATE?
Of the 635 reports, 1 (0.2%) resulted in death, 267 (42.0%) required hospitalization, and 13 (2.0%) were considered life-threatening.
Is Deafness Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 635 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Deafness?
ADALIMUMAB (1,300)
ETANERCEPT (629)
SACUBITRIL\VALSARTAN (471)
APIXABAN (455)
LENALIDOMIDE (397)
TOFACITINIB (388)
CISPLATIN (344)
AMIKACIN (320)
ATORVASTATIN (308)
LEFLUNOMIDE (282)
Which METHOTREXATE Alternatives Have Lower Deafness Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA