Does IBRUTINIB Cause Herpes zoster? 398 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 398 reports of Herpes zoster have been filed in association with IBRUTINIB (Imbruvica). This represents 0.5% of all adverse event reports for IBRUTINIB.
398
Reports of Herpes zoster with IBRUTINIB
0.5%
of all IBRUTINIB reports
32
Deaths
165
Hospitalizations
How Dangerous Is Herpes zoster From IBRUTINIB?
Of the 398 reports, 32 (8.0%) resulted in death, 165 (41.5%) required hospitalization, and 9 (2.3%) were considered life-threatening.
Is Herpes zoster Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for IBRUTINIB. However, 398 reports have been filed with the FAERS database.
What Other Side Effects Does IBRUTINIB Cause?
Death (8,007)
Off label use (5,446)
Fatigue (4,479)
Diarrhoea (3,903)
Atrial fibrillation (3,671)
Pneumonia (3,015)
Incorrect dose administered (2,752)
Contusion (2,712)
Fall (2,375)
Asthenia (2,200)
What Other Drugs Cause Herpes zoster?
ADALIMUMAB (3,783)
TOFACITINIB (3,575)
ETANERCEPT (3,129)
METHOTREXATE (2,589)
RITUXIMAB (2,228)
INFLIXIMAB (2,081)
LENALIDOMIDE (1,762)
TOCILIZUMAB (1,676)
OCRELIZUMAB (1,433)
ABATACEPT (1,395)
Which IBRUTINIB Alternatives Have Lower Herpes zoster Risk?
IBRUTINIB vs IBUPROFEN
IBRUTINIB vs IBUPROFEN LYSINE
IBRUTINIB vs IBUPROFEN UNKNOWN PRODUCT
IBRUTINIB vs IBUPROFEN\IBUPROFEN
IBRUTINIB vs IBUPROFEN\PHENYLEPHRINE