Does IBRUTINIB Cause Hypocalcaemia? 58 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 58 reports of Hypocalcaemia have been filed in association with IBRUTINIB (Imbruvica). This represents 0.1% of all adverse event reports for IBRUTINIB.
58
Reports of Hypocalcaemia with IBRUTINIB
0.1%
of all IBRUTINIB reports
19
Deaths
26
Hospitalizations
How Dangerous Is Hypocalcaemia From IBRUTINIB?
Of the 58 reports, 19 (32.8%) resulted in death, 26 (44.8%) required hospitalization, and 4 (6.9%) were considered life-threatening.
Is Hypocalcaemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for IBRUTINIB. However, 58 reports have been filed with the FAERS database.
What Other Side Effects Does IBRUTINIB Cause?
Death (8,007)
Off label use (5,446)
Fatigue (4,479)
Diarrhoea (3,903)
Atrial fibrillation (3,671)
Pneumonia (3,015)
Incorrect dose administered (2,752)
Contusion (2,712)
Fall (2,375)
Asthenia (2,200)
What Other Drugs Cause Hypocalcaemia?
DENOSUMAB (2,345)
OMEPRAZOLE (966)
PANTOPRAZOLE (935)
PARATHYROID HORMONE (784)
ZOLEDRONIC ACID (513)
CINACALCET (468)
ESOMEPRAZOLE (451)
FUROSEMIDE (429)
DEXAMETHASONE (368)
PREDNISONE (352)
Which IBRUTINIB Alternatives Have Lower Hypocalcaemia Risk?
IBRUTINIB vs IBUPROFEN
IBRUTINIB vs IBUPROFEN LYSINE
IBRUTINIB vs IBUPROFEN UNKNOWN PRODUCT
IBRUTINIB vs IBUPROFEN\IBUPROFEN
IBRUTINIB vs IBUPROFEN\PHENYLEPHRINE