Does IBRUTINIB Cause Mitral valve incompetence? 42 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 42 reports of Mitral valve incompetence have been filed in association with IBRUTINIB (Imbruvica). This represents 0.1% of all adverse event reports for IBRUTINIB.
42
Reports of Mitral valve incompetence with IBRUTINIB
0.1%
of all IBRUTINIB reports
2
Deaths
30
Hospitalizations
How Dangerous Is Mitral valve incompetence From IBRUTINIB?
Of the 42 reports, 2 (4.8%) resulted in death, 30 (71.4%) required hospitalization, and 4 (9.5%) were considered life-threatening.
Is Mitral valve incompetence Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for IBRUTINIB. However, 42 reports have been filed with the FAERS database.
What Other Side Effects Does IBRUTINIB Cause?
Death (8,007)
Off label use (5,446)
Fatigue (4,479)
Diarrhoea (3,903)
Atrial fibrillation (3,671)
Pneumonia (3,015)
Incorrect dose administered (2,752)
Contusion (2,712)
Fall (2,375)
Asthenia (2,200)
What Other Drugs Cause Mitral valve incompetence?
SACUBITRIL\VALSARTAN (437)
BISOPROLOL (370)
ASPIRIN (282)
FENFLURAMINE (276)
PANTOPRAZOLE (264)
FUROSEMIDE (252)
ATORVASTATIN (222)
ADALIMUMAB (212)
VALSARTAN (185)
AMLODIPINE (178)
Which IBRUTINIB Alternatives Have Lower Mitral valve incompetence Risk?
IBRUTINIB vs IBUPROFEN
IBRUTINIB vs IBUPROFEN LYSINE
IBRUTINIB vs IBUPROFEN UNKNOWN PRODUCT
IBRUTINIB vs IBUPROFEN\IBUPROFEN
IBRUTINIB vs IBUPROFEN\PHENYLEPHRINE