Does IBRUTINIB Cause Nephrolithiasis? 319 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 319 reports of Nephrolithiasis have been filed in association with IBRUTINIB (Imbruvica). This represents 0.4% of all adverse event reports for IBRUTINIB.
319
Reports of Nephrolithiasis with IBRUTINIB
0.4%
of all IBRUTINIB reports
4
Deaths
160
Hospitalizations
How Dangerous Is Nephrolithiasis From IBRUTINIB?
Of the 319 reports, 4 (1.3%) resulted in death, 160 (50.2%) required hospitalization.
Is Nephrolithiasis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for IBRUTINIB. However, 319 reports have been filed with the FAERS database.
What Other Side Effects Does IBRUTINIB Cause?
Death (8,007)
Off label use (5,446)
Fatigue (4,479)
Diarrhoea (3,903)
Atrial fibrillation (3,671)
Pneumonia (3,015)
Incorrect dose administered (2,752)
Contusion (2,712)
Fall (2,375)
Asthenia (2,200)
What Other Drugs Cause Nephrolithiasis?
ADALIMUMAB (2,416)
ETANERCEPT (1,292)
INFLIXIMAB (981)
METHOTREXATE (979)
ABATACEPT (788)
TOPIRAMATE (768)
CERTOLIZUMAB PEGOL (735)
RITUXIMAB (709)
TOFACITINIB (699)
SODIUM OXYBATE (698)
Which IBRUTINIB Alternatives Have Lower Nephrolithiasis Risk?
IBRUTINIB vs IBUPROFEN
IBRUTINIB vs IBUPROFEN LYSINE
IBRUTINIB vs IBUPROFEN UNKNOWN PRODUCT
IBRUTINIB vs IBUPROFEN\IBUPROFEN
IBRUTINIB vs IBUPROFEN\PHENYLEPHRINE