Does IBUPROFEN Cause Pemphigus? 273 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 273 reports of Pemphigus have been filed in association with IBUPROFEN (equate ibuprofen). This represents 0.3% of all adverse event reports for IBUPROFEN.
273
Reports of Pemphigus with IBUPROFEN
0.3%
of all IBUPROFEN reports
219
Deaths
257
Hospitalizations
How Dangerous Is Pemphigus From IBUPROFEN?
Of the 273 reports, 219 (80.2%) resulted in death, 257 (94.1%) required hospitalization, and 233 (85.3%) were considered life-threatening.
Is Pemphigus Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for IBUPROFEN. However, 273 reports have been filed with the FAERS database.
What Other Side Effects Does IBUPROFEN Cause?
Drug ineffective (9,352)
Drug hypersensitivity (5,269)
Nausea (4,129)
Vomiting (4,116)
Acute kidney injury (3,639)
Product use in unapproved indication (3,596)
Toxicity to various agents (3,584)
Off label use (3,556)
Intentional overdose (3,185)
Headache (3,010)
What Other Drugs Cause Pemphigus?
RITUXIMAB (8,574)
ABATACEPT (8,441)
METHOTREXATE (8,414)
PREDNISONE (8,260)
LEFLUNOMIDE (8,252)
TOCILIZUMAB (8,210)
FOLIC ACID (8,128)
ADALIMUMAB (8,079)
CETIRIZINE (8,063)
HYDROXYCHLOROQUINE (8,051)
Which IBUPROFEN Alternatives Have Lower Pemphigus Risk?
IBUPROFEN vs IBUPROFEN LYSINE
IBUPROFEN vs IBUPROFEN UNKNOWN PRODUCT
IBUPROFEN vs IBUPROFEN\IBUPROFEN
IBUPROFEN vs IBUPROFEN\PHENYLEPHRINE
IBUPROFEN vs IBUPROFEN\PSEUDOEPHEDRINE