IMIPENEM for Prophylaxis: Side Effects & Safety Data
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There are 23 adverse event reports in the FDA FAERS database where IMIPENEM was used for Prophylaxis.
Most Reported Side Effects for IMIPENEM
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Drug ineffective | 351 | 18.7% | 156 | 176 |
| Off label use | 202 | 10.8% | 74 | 110 |
| Condition aggravated | 138 | 7.3% | 38 | 55 |
| Vomiting | 137 | 7.3% | 38 | 60 |
| Drug resistance | 117 | 6.2% | 27 | 44 |
| Nausea | 111 | 5.9% | 12 | 47 |
| Dyspnoea | 97 | 5.2% | 58 | 68 |
| Diarrhoea | 90 | 4.8% | 50 | 43 |
| Pyrexia | 90 | 4.8% | 30 | 61 |
| Product use in unapproved indication | 85 | 4.5% | 12 | 22 |
| Thrombocytopenia | 84 | 4.5% | 9 | 33 |
| Treatment failure | 82 | 4.4% | 48 | 38 |
| Multiple organ dysfunction syndrome | 80 | 4.3% | 63 | 35 |
| Electrocardiogram qt prolonged | 76 | 4.0% | 14 | 38 |
| Acute kidney injury | 71 | 3.8% | 23 | 42 |
Other Indications for IMIPENEM
Tuberculosis (241)
Product used for unknown indication (233)
Mycobacterium abscessus infection (178)
Antibiotic therapy (114)
Pulmonary tuberculosis (92)
Nocardiosis (85)
Infection (64)
Pneumonia (56)
Klebsiella infection (37)
Sepsis (37)
Other Drugs Used for Prophylaxis
PEGFILGRASTIM (7,424)
HUMAN C1-ESTERASE INHIBITOR (5,950)
DENOSUMAB (4,541)
SULFAMETHOXAZOLE\TRIMETHOPRIM (3,197)
ASPIRIN (2,083)
VALACYCLOVIR (1,574)
PANTOPRAZOLE (1,502)
VARICELLA-ZOSTER VIRUS STRAIN OKA/MERCK LIVE ANTIGEN (1,444)
CLOPIDOGREL BISULFATE (1,296)
ENOXAPARIN (1,278)