IRINOTECAN for Rectal cancer: Side Effects & Safety Data
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There are 985 adverse event reports in the FDA FAERS database where IRINOTECAN was used for Rectal cancer.
Most Reported Side Effects for IRINOTECAN
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Diarrhoea | 4,157 | 14.9% | 558 | 1,893 |
| Neutropenia | 2,533 | 9.1% | 343 | 655 |
| Nausea | 2,374 | 8.5% | 228 | 1,029 |
| Disease progression | 2,018 | 7.2% | 628 | 271 |
| Off label use | 2,018 | 7.2% | 345 | 630 |
| Vomiting | 1,944 | 7.0% | 225 | 1,057 |
| Fatigue | 1,515 | 5.4% | 205 | 557 |
| Febrile neutropenia | 1,357 | 4.9% | 224 | 805 |
| Anaemia | 1,231 | 4.4% | 195 | 462 |
| Thrombocytopenia | 1,214 | 4.3% | 188 | 305 |
| Neuropathy peripheral | 1,207 | 4.3% | 75 | 183 |
| Asthenia | 1,154 | 4.1% | 157 | 557 |
| Pyrexia | 1,145 | 4.1% | 124 | 831 |
| Drug ineffective | 1,133 | 4.1% | 277 | 238 |
| Decreased appetite | 1,119 | 4.0% | 165 | 532 |
Other Indications for IRINOTECAN
Colorectal cancer metastatic (4,655)
Pancreatic carcinoma (2,128)
Colon cancer (2,105)
Product used for unknown indication (2,042)
Colorectal cancer (1,446)
Adenocarcinoma of colon (1,235)
Pancreatic carcinoma metastatic (977)
Adenocarcinoma pancreas (908)
Colon cancer metastatic (841)
Metastases to liver (622)
Other Drugs Used for Rectal cancer
CAPECITABINE (2,976)
OXALIPLATIN (2,402)
FLUOROURACIL (1,610)
BEVACIZUMAB (1,546)
TIPIRACIL\TRIFLURIDINE (1,297)
LEUCOVORIN (660)
CETUXIMAB (542)
REGORAFENIB (505)
PANITUMUMAB (374)
FRUQUINTINIB (367)