Does IRINOTECAN Cause Off label use? 2,018 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 2,018 reports of Off label use have been filed in association with IRINOTECAN (Irinotecan Hydrochloride). This represents 7.2% of all adverse event reports for IRINOTECAN.
2,018
Reports of Off label use with IRINOTECAN
7.2%
of all IRINOTECAN reports
345
Deaths
630
Hospitalizations
How Dangerous Is Off label use From IRINOTECAN?
Of the 2,018 reports, 345 (17.1%) resulted in death, 630 (31.2%) required hospitalization, and 119 (5.9%) were considered life-threatening.
Is Off label use Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for IRINOTECAN. However, 2,018 reports have been filed with the FAERS database.
What Other Side Effects Does IRINOTECAN Cause?
Diarrhoea (4,157)
Neutropenia (2,533)
Nausea (2,374)
Disease progression (2,018)
Vomiting (1,944)
Fatigue (1,515)
Febrile neutropenia (1,357)
Anaemia (1,231)
Thrombocytopenia (1,214)
Neuropathy peripheral (1,207)
What Other Drugs Cause Off label use?
RITUXIMAB (39,751)
INFLIXIMAB (34,801)
DENOSUMAB (34,612)
METHOTREXATE (24,020)
VEDOLIZUMAB (21,017)
ETANERCEPT (20,178)
TOCILIZUMAB (18,256)
PREDNISONE (17,867)
LENALIDOMIDE (17,017)
ADALIMUMAB (16,417)
Which IRINOTECAN Alternatives Have Lower Off label use Risk?
IRINOTECAN vs IRON
IRINOTECAN vs IRON DEXTRAN
IRINOTECAN vs IRON ISOMALTOSIDE 1000
IRINOTECAN vs IRON POLYMALTOSE
IRINOTECAN vs IRON SUCROSE