Does IRINOTECAN Cause Ataxia? 21 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 21 reports of Ataxia have been filed in association with IRINOTECAN (Irinotecan Hydrochloride). This represents 0.1% of all adverse event reports for IRINOTECAN.
21
Reports of Ataxia with IRINOTECAN
0.1%
of all IRINOTECAN reports
6
Deaths
9
Hospitalizations
How Dangerous Is Ataxia From IRINOTECAN?
Of the 21 reports, 6 (28.6%) resulted in death, 9 (42.9%) required hospitalization, and 5 (23.8%) were considered life-threatening.
Is Ataxia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for IRINOTECAN. However, 21 reports have been filed with the FAERS database.
What Other Side Effects Does IRINOTECAN Cause?
Diarrhoea (4,157)
Neutropenia (2,533)
Nausea (2,374)
Disease progression (2,018)
Off label use (2,018)
Vomiting (1,944)
Fatigue (1,515)
Febrile neutropenia (1,357)
Anaemia (1,231)
Thrombocytopenia (1,214)
What Other Drugs Cause Ataxia?
LAMOTRIGINE (535)
PHENYTOIN (406)
FINGOLIMOD (393)
LEVETIRACETAM (309)
GABAPENTIN (297)
CARBAMAZEPINE (272)
METRONIDAZOLE (260)
LITHIUM (250)
LORAZEPAM (235)
CLONAZEPAM (233)
Which IRINOTECAN Alternatives Have Lower Ataxia Risk?
IRINOTECAN vs IRON
IRINOTECAN vs IRON DEXTRAN
IRINOTECAN vs IRON ISOMALTOSIDE 1000
IRINOTECAN vs IRON POLYMALTOSE
IRINOTECAN vs IRON SUCROSE