Does IRINOTECAN Cause Colitis? 286 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 286 reports of Colitis have been filed in association with IRINOTECAN (Irinotecan Hydrochloride). This represents 1.0% of all adverse event reports for IRINOTECAN.
286
Reports of Colitis with IRINOTECAN
1.0%
of all IRINOTECAN reports
16
Deaths
208
Hospitalizations
How Dangerous Is Colitis From IRINOTECAN?
Of the 286 reports, 16 (5.6%) resulted in death, 208 (72.7%) required hospitalization, and 38 (13.3%) were considered life-threatening.
Is Colitis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for IRINOTECAN. However, 286 reports have been filed with the FAERS database.
What Other Side Effects Does IRINOTECAN Cause?
Diarrhoea (4,157)
Neutropenia (2,533)
Nausea (2,374)
Disease progression (2,018)
Off label use (2,018)
Vomiting (1,944)
Fatigue (1,515)
Febrile neutropenia (1,357)
Anaemia (1,231)
Thrombocytopenia (1,214)
What Other Drugs Cause Colitis?
ADALIMUMAB (3,043)
NIVOLUMAB (2,123)
IPILIMUMAB (1,988)
PEMBROLIZUMAB (1,638)
INFLIXIMAB (1,254)
METHOTREXATE (1,166)
PREDNISONE (1,100)
VEDOLIZUMAB (1,077)
CARBOPLATIN (993)
MESALAMINE (839)
Which IRINOTECAN Alternatives Have Lower Colitis Risk?
IRINOTECAN vs IRON
IRINOTECAN vs IRON DEXTRAN
IRINOTECAN vs IRON ISOMALTOSIDE 1000
IRINOTECAN vs IRON POLYMALTOSE
IRINOTECAN vs IRON SUCROSE