Does IRINOTECAN Cause Enterocolitis? 85 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 85 reports of Enterocolitis have been filed in association with IRINOTECAN (Irinotecan Hydrochloride). This represents 0.3% of all adverse event reports for IRINOTECAN.
85
Reports of Enterocolitis with IRINOTECAN
0.3%
of all IRINOTECAN reports
8
Deaths
65
Hospitalizations
How Dangerous Is Enterocolitis From IRINOTECAN?
Of the 85 reports, 8 (9.4%) resulted in death, 65 (76.5%) required hospitalization, and 11 (12.9%) were considered life-threatening.
Is Enterocolitis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for IRINOTECAN. However, 85 reports have been filed with the FAERS database.
What Other Side Effects Does IRINOTECAN Cause?
Diarrhoea (4,157)
Neutropenia (2,533)
Nausea (2,374)
Disease progression (2,018)
Off label use (2,018)
Vomiting (1,944)
Fatigue (1,515)
Febrile neutropenia (1,357)
Anaemia (1,231)
Thrombocytopenia (1,214)
What Other Drugs Cause Enterocolitis?
NIVOLUMAB (471)
IPILIMUMAB (321)
CAPECITABINE (291)
OXALIPLATIN (227)
METHOTREXATE (191)
PEMBROLIZUMAB (180)
RITUXIMAB (174)
DEXAMETHASONE (162)
BEVACIZUMAB (161)
CARBOPLATIN (160)
Which IRINOTECAN Alternatives Have Lower Enterocolitis Risk?
IRINOTECAN vs IRON
IRINOTECAN vs IRON DEXTRAN
IRINOTECAN vs IRON ISOMALTOSIDE 1000
IRINOTECAN vs IRON POLYMALTOSE
IRINOTECAN vs IRON SUCROSE