Does IRINOTECAN Cause Hydronephrosis? 53 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 53 reports of Hydronephrosis have been filed in association with IRINOTECAN (Irinotecan Hydrochloride). This represents 0.2% of all adverse event reports for IRINOTECAN.
53
Reports of Hydronephrosis with IRINOTECAN
0.2%
of all IRINOTECAN reports
17
Deaths
33
Hospitalizations
How Dangerous Is Hydronephrosis From IRINOTECAN?
Of the 53 reports, 17 (32.1%) resulted in death, 33 (62.3%) required hospitalization, and 3 (5.7%) were considered life-threatening.
Is Hydronephrosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for IRINOTECAN. However, 53 reports have been filed with the FAERS database.
What Other Side Effects Does IRINOTECAN Cause?
Diarrhoea (4,157)
Neutropenia (2,533)
Nausea (2,374)
Disease progression (2,018)
Off label use (2,018)
Vomiting (1,944)
Fatigue (1,515)
Febrile neutropenia (1,357)
Anaemia (1,231)
Thrombocytopenia (1,214)
What Other Drugs Cause Hydronephrosis?
TACROLIMUS (260)
PREDNISONE (229)
MYCOPHENOLATE MOFETIL (202)
LANSOPRAZOLE (194)
RITUXIMAB (187)
BEVACIZUMAB (177)
OMEPRAZOLE (158)
CYCLOPHOSPHAMIDE (151)
CARBOPLATIN (145)
PREDNISOLONE (145)
Which IRINOTECAN Alternatives Have Lower Hydronephrosis Risk?
IRINOTECAN vs IRON
IRINOTECAN vs IRON DEXTRAN
IRINOTECAN vs IRON ISOMALTOSIDE 1000
IRINOTECAN vs IRON POLYMALTOSE
IRINOTECAN vs IRON SUCROSE