Does IRINOTECAN Cause Intestinal ischaemia? 27 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 27 reports of Intestinal ischaemia have been filed in association with IRINOTECAN (Irinotecan Hydrochloride). This represents 0.1% of all adverse event reports for IRINOTECAN.
27
Reports of Intestinal ischaemia with IRINOTECAN
0.1%
of all IRINOTECAN reports
18
Deaths
21
Hospitalizations
How Dangerous Is Intestinal ischaemia From IRINOTECAN?
Of the 27 reports, 18 (66.7%) resulted in death, 21 (77.8%) required hospitalization, and 11 (40.7%) were considered life-threatening.
Is Intestinal ischaemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for IRINOTECAN. However, 27 reports have been filed with the FAERS database.
What Other Side Effects Does IRINOTECAN Cause?
Diarrhoea (4,157)
Neutropenia (2,533)
Nausea (2,374)
Disease progression (2,018)
Off label use (2,018)
Vomiting (1,944)
Fatigue (1,515)
Febrile neutropenia (1,357)
Anaemia (1,231)
Thrombocytopenia (1,214)
What Other Drugs Cause Intestinal ischaemia?
PROPOFOL (128)
FLUOROURACIL (119)
OXALIPLATIN (119)
METHYLPREDNISOLONE (109)
CLOZAPINE (93)
DOCETAXEL (89)
AMLODIPINE (87)
METHOTREXATE (87)
PREDNISONE (83)
MIDAZOLAM (81)
Which IRINOTECAN Alternatives Have Lower Intestinal ischaemia Risk?
IRINOTECAN vs IRON
IRINOTECAN vs IRON DEXTRAN
IRINOTECAN vs IRON ISOMALTOSIDE 1000
IRINOTECAN vs IRON POLYMALTOSE
IRINOTECAN vs IRON SUCROSE