Does IRINOTECAN Cause Leukopenia? 696 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 696 reports of Leukopenia have been filed in association with IRINOTECAN (Irinotecan Hydrochloride). This represents 2.5% of all adverse event reports for IRINOTECAN.
696
Reports of Leukopenia with IRINOTECAN
2.5%
of all IRINOTECAN reports
64
Deaths
182
Hospitalizations
How Dangerous Is Leukopenia From IRINOTECAN?
Of the 696 reports, 64 (9.2%) resulted in death, 182 (26.1%) required hospitalization, and 30 (4.3%) were considered life-threatening.
Is Leukopenia Listed in the Official Label?
Yes, Leukopenia is listed as a known adverse reaction in the official FDA drug label for IRINOTECAN.
What Other Side Effects Does IRINOTECAN Cause?
Diarrhoea (4,157)
Neutropenia (2,533)
Nausea (2,374)
Disease progression (2,018)
Off label use (2,018)
Vomiting (1,944)
Fatigue (1,515)
Febrile neutropenia (1,357)
Anaemia (1,231)
Thrombocytopenia (1,214)
What Other Drugs Cause Leukopenia?
METHOTREXATE (2,694)
CYCLOPHOSPHAMIDE (2,482)
RITUXIMAB (2,191)
CLOZAPINE (2,036)
PREDNISONE (1,725)
DOXORUBICIN (1,696)
PACLITAXEL (1,649)
CARBOPLATIN (1,624)
DEXAMETHASONE (1,542)
MYCOPHENOLATE MOFETIL (1,491)
Which IRINOTECAN Alternatives Have Lower Leukopenia Risk?
IRINOTECAN vs IRON
IRINOTECAN vs IRON DEXTRAN
IRINOTECAN vs IRON ISOMALTOSIDE 1000
IRINOTECAN vs IRON POLYMALTOSE
IRINOTECAN vs IRON SUCROSE