Does IRINOTECAN Cause Paralysis? 23 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 23 reports of Paralysis have been filed in association with IRINOTECAN (Irinotecan Hydrochloride). This represents 0.1% of all adverse event reports for IRINOTECAN.
23
Reports of Paralysis with IRINOTECAN
0.1%
of all IRINOTECAN reports
4
Deaths
14
Hospitalizations
How Dangerous Is Paralysis From IRINOTECAN?
Of the 23 reports, 4 (17.4%) resulted in death, 14 (60.9%) required hospitalization, and 2 (8.7%) were considered life-threatening.
Is Paralysis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for IRINOTECAN. However, 23 reports have been filed with the FAERS database.
What Other Side Effects Does IRINOTECAN Cause?
Diarrhoea (4,157)
Neutropenia (2,533)
Nausea (2,374)
Disease progression (2,018)
Off label use (2,018)
Vomiting (1,944)
Fatigue (1,515)
Febrile neutropenia (1,357)
Anaemia (1,231)
Thrombocytopenia (1,214)
What Other Drugs Cause Paralysis?
ADALIMUMAB (275)
INTERFERON BETA-1A (181)
METHOTREXATE (181)
PREGABALIN (171)
RITUXIMAB (166)
ATORVASTATIN (160)
DIMETHYL (156)
FINGOLIMOD (145)
NATALIZUMAB (136)
ETANERCEPT (134)
Which IRINOTECAN Alternatives Have Lower Paralysis Risk?
IRINOTECAN vs IRON
IRINOTECAN vs IRON DEXTRAN
IRINOTECAN vs IRON ISOMALTOSIDE 1000
IRINOTECAN vs IRON POLYMALTOSE
IRINOTECAN vs IRON SUCROSE