Does IRINOTECAN Cause Sinus bradycardia? 18 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 18 reports of Sinus bradycardia have been filed in association with IRINOTECAN (Irinotecan Hydrochloride). This represents 0.1% of all adverse event reports for IRINOTECAN.
18
Reports of Sinus bradycardia with IRINOTECAN
0.1%
of all IRINOTECAN reports
1
Deaths
5
Hospitalizations
How Dangerous Is Sinus bradycardia From IRINOTECAN?
Of the 18 reports, 1 (5.6%) resulted in death, 5 (27.8%) required hospitalization, and 1 (5.6%) were considered life-threatening.
Is Sinus bradycardia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for IRINOTECAN. However, 18 reports have been filed with the FAERS database.
What Other Side Effects Does IRINOTECAN Cause?
Diarrhoea (4,157)
Neutropenia (2,533)
Nausea (2,374)
Disease progression (2,018)
Off label use (2,018)
Vomiting (1,944)
Fatigue (1,515)
Febrile neutropenia (1,357)
Anaemia (1,231)
Thrombocytopenia (1,214)
What Other Drugs Cause Sinus bradycardia?
BISOPROLOL (479)
METOPROLOL (342)
AMLODIPINE (339)
AMIODARONE (282)
FINGOLIMOD (243)
ATENOLOL (222)
DONEPEZIL (194)
CARVEDILOL (184)
DIGOXIN (156)
OLANZAPINE (132)
Which IRINOTECAN Alternatives Have Lower Sinus bradycardia Risk?
IRINOTECAN vs IRON
IRINOTECAN vs IRON DEXTRAN
IRINOTECAN vs IRON ISOMALTOSIDE 1000
IRINOTECAN vs IRON POLYMALTOSE
IRINOTECAN vs IRON SUCROSE