Does IRINOTECAN Cause Transaminases increased? 124 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 124 reports of Transaminases increased have been filed in association with IRINOTECAN (Irinotecan Hydrochloride). This represents 0.4% of all adverse event reports for IRINOTECAN.
124
Reports of Transaminases increased with IRINOTECAN
0.4%
of all IRINOTECAN reports
17
Deaths
16
Hospitalizations
How Dangerous Is Transaminases increased From IRINOTECAN?
Of the 124 reports, 17 (13.7%) resulted in death, 16 (12.9%) required hospitalization, and 3 (2.4%) were considered life-threatening.
Is Transaminases increased Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for IRINOTECAN. However, 124 reports have been filed with the FAERS database.
What Other Side Effects Does IRINOTECAN Cause?
Diarrhoea (4,157)
Neutropenia (2,533)
Nausea (2,374)
Disease progression (2,018)
Off label use (2,018)
Vomiting (1,944)
Fatigue (1,515)
Febrile neutropenia (1,357)
Anaemia (1,231)
Thrombocytopenia (1,214)
What Other Drugs Cause Transaminases increased?
METHOTREXATE (1,236)
ACETAMINOPHEN (929)
ATORVASTATIN (472)
RITUXIMAB (448)
CYCLOPHOSPHAMIDE (401)
PREDNISONE (362)
ADALIMUMAB (340)
PACLITAXEL (333)
ROSUVASTATIN (324)
CARBOPLATIN (319)
Which IRINOTECAN Alternatives Have Lower Transaminases increased Risk?
IRINOTECAN vs IRON
IRINOTECAN vs IRON DEXTRAN
IRINOTECAN vs IRON ISOMALTOSIDE 1000
IRINOTECAN vs IRON POLYMALTOSE
IRINOTECAN vs IRON SUCROSE