Does ISONIAZID Cause Disseminated tuberculosis? 117 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 117 reports of Disseminated tuberculosis have been filed in association with ISONIAZID (Isoniazid). This represents 1.5% of all adverse event reports for ISONIAZID.
117
Reports of Disseminated tuberculosis with ISONIAZID
1.5%
of all ISONIAZID reports
31
Deaths
72
Hospitalizations
How Dangerous Is Disseminated tuberculosis From ISONIAZID?
Of the 117 reports, 31 (26.5%) resulted in death, 72 (61.5%) required hospitalization, and 16 (13.7%) were considered life-threatening.
Is Disseminated tuberculosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for ISONIAZID. However, 117 reports have been filed with the FAERS database.
What Other Side Effects Does ISONIAZID Cause?
Drug-induced liver injury (766)
Drug ineffective (607)
Drug reaction with eosinophilia and systemic symptoms (550)
Pyrexia (517)
Nausea (488)
Paradoxical drug reaction (433)
Off label use (406)
Drug resistance (367)
Hepatotoxicity (349)
Headache (324)
What Other Drugs Cause Disseminated tuberculosis?
INFLIXIMAB (341)
ADALIMUMAB (258)
PREDNISONE (179)
PREDNISOLONE (176)
TACROLIMUS (174)
METHOTREXATE (170)
MYCOPHENOLATE MOFETIL (144)
ETHAMBUTOL (114)
RIFAMPIN (113)
PYRAZINAMIDE (109)
Which ISONIAZID Alternatives Have Lower Disseminated tuberculosis Risk?
ISONIAZID vs ISONIAZID\PYRAZINAMIDE\RIFAMPIN
ISONIAZID vs ISONIAZID\PYRIDOXINE\SULFAMETHOXAZOLE\TRIMETHOPRIM
ISONIAZID vs ISONIAZID\RIFAMPIN
ISONIAZID vs ISOPROPANOLAMINE
ISONIAZID vs ISOPROPYL ALCOHOL