Does ISONIAZID Cause Pyrexia? 517 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 517 reports of Pyrexia have been filed in association with ISONIAZID (Isoniazid). This represents 6.8% of all adverse event reports for ISONIAZID.
517
Reports of Pyrexia with ISONIAZID
6.8%
of all ISONIAZID reports
34
Deaths
360
Hospitalizations
How Dangerous Is Pyrexia From ISONIAZID?
Of the 517 reports, 34 (6.6%) resulted in death, 360 (69.6%) required hospitalization, and 36 (7.0%) were considered life-threatening.
Is Pyrexia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for ISONIAZID. However, 517 reports have been filed with the FAERS database.
What Other Side Effects Does ISONIAZID Cause?
Drug-induced liver injury (766)
Drug ineffective (607)
Drug reaction with eosinophilia and systemic symptoms (550)
Nausea (488)
Paradoxical drug reaction (433)
Off label use (406)
Drug resistance (367)
Hepatotoxicity (349)
Headache (324)
Vomiting (311)
What Other Drugs Cause Pyrexia?
ADALIMUMAB (12,160)
METHOTREXATE (10,158)
RITUXIMAB (10,061)
PREDNISONE (8,141)
ETANERCEPT (7,626)
INFLIXIMAB (6,560)
ACETAMINOPHEN (6,414)
CYCLOPHOSPHAMIDE (6,126)
TOCILIZUMAB (5,529)
LENALIDOMIDE (5,496)
Which ISONIAZID Alternatives Have Lower Pyrexia Risk?
ISONIAZID vs ISONIAZID\PYRAZINAMIDE\RIFAMPIN
ISONIAZID vs ISONIAZID\PYRIDOXINE\SULFAMETHOXAZOLE\TRIMETHOPRIM
ISONIAZID vs ISONIAZID\RIFAMPIN
ISONIAZID vs ISOPROPANOLAMINE
ISONIAZID vs ISOPROPYL ALCOHOL