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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Pyrexia: Which Medications Cause It? (242,192 Reports Across 2,749 Drugs)

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Pyrexia has been reported as an adverse event with 2,749 different drugs in the FDA's FAERS database, with 242,192 total reports. 20,146 of these reports resulted in death.The drugs most commonly associated with Pyrexia are ADALIMUMAB, METHOTREXATE, and RITUXIMAB.

242,192
Total Reports
2,749
Drugs Involved
20,146
Deaths
120,306
Hospitalizations
50.8 yrs
Average Patient Age
58.0% / 42.0%
Female / Male

Which Drugs Cause Pyrexia Most Often?

Drug Reports % of Drug Reports Deaths Hosp. Life-Threat.
ADALIMUMAB 12,160 2.4% 1,534 5,641 1,533
METHOTREXATE 10,158 4.0% 1,783 5,860 2,114
RITUXIMAB 10,061 5.6% 2,054 5,833 1,988
PREDNISONE 8,141 5.1% 1,636 5,176 1,931
ETANERCEPT 7,626 2.1% 1,182 2,387 1,123
INFLIXIMAB 6,560 4.7% 1,231 3,205 1,383
ACETAMINOPHEN 6,414 4.7% 1,527 3,292 1,549
CYCLOPHOSPHAMIDE 6,126 4.8% 832 4,228 681
TOCILIZUMAB 5,529 5.6% 1,497 2,563 1,443
LENALIDOMIDE 5,496 1.6% 432 3,263 188
ABATACEPT 5,045 4.3% 1,163 2,236 1,446
SECUKINUMAB 4,856 3.2% 1,141 2,500 1,542
TOFACITINIB 4,693 3.0% 1,044 2,120 1,231
DEXAMETHASONE 4,639 3.7% 766 3,260 500
CERTOLIZUMAB PEGOL 4,418 4.5% 1,048 1,978 1,236
SULFAMETHOXAZOLE\TRIMETHOPRIM 4,364 11.2% 970 2,581 997
HUMAN IMMUNOGLOBULIN G 4,076 5.8% 275 1,583 183
LEFLUNOMIDE 3,933 7.0% 1,100 2,073 1,387
DUPILUMAB 3,895 1.0% 12 575 27
DABRAFENIB 3,788 19.6% 352 1,599 142

View all 2,749 drugs →

Top 3 Drugs Associated With Pyrexia

12,160 reports
10,158 reports
10,061 reports

Related Side Effects

Drug ineffective (1,049,718) Off label use (762,782) Death (660,423) Fatigue (599,248) Nausea (562,301) Diarrhoea (491,550) Pain (471,975) Headache (460,069) Dyspnoea (409,496) Dizziness (352,922)