Does ISONIAZID Cause Leukopenia? 58 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 58 reports of Leukopenia have been filed in association with ISONIAZID (Isoniazid). This represents 0.8% of all adverse event reports for ISONIAZID.
58
Reports of Leukopenia with ISONIAZID
0.8%
of all ISONIAZID reports
2
Deaths
20
Hospitalizations
How Dangerous Is Leukopenia From ISONIAZID?
Of the 58 reports, 2 (3.4%) resulted in death, 20 (34.5%) required hospitalization, and 5 (8.6%) were considered life-threatening.
Is Leukopenia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for ISONIAZID. However, 58 reports have been filed with the FAERS database.
What Other Side Effects Does ISONIAZID Cause?
Drug-induced liver injury (766)
Drug ineffective (607)
Drug reaction with eosinophilia and systemic symptoms (550)
Pyrexia (517)
Nausea (488)
Paradoxical drug reaction (433)
Off label use (406)
Drug resistance (367)
Hepatotoxicity (349)
Headache (324)
What Other Drugs Cause Leukopenia?
METHOTREXATE (2,694)
CYCLOPHOSPHAMIDE (2,482)
RITUXIMAB (2,191)
CLOZAPINE (2,036)
PREDNISONE (1,725)
DOXORUBICIN (1,696)
PACLITAXEL (1,649)
CARBOPLATIN (1,624)
DEXAMETHASONE (1,542)
MYCOPHENOLATE MOFETIL (1,491)
Which ISONIAZID Alternatives Have Lower Leukopenia Risk?
ISONIAZID vs ISONIAZID\PYRAZINAMIDE\RIFAMPIN
ISONIAZID vs ISONIAZID\PYRIDOXINE\SULFAMETHOXAZOLE\TRIMETHOPRIM
ISONIAZID vs ISONIAZID\RIFAMPIN
ISONIAZID vs ISOPROPANOLAMINE
ISONIAZID vs ISOPROPYL ALCOHOL