Does ISONIAZID Cause Neutropenia? 101 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 101 reports of Neutropenia have been filed in association with ISONIAZID (Isoniazid). This represents 1.3% of all adverse event reports for ISONIAZID.
101
Reports of Neutropenia with ISONIAZID
1.3%
of all ISONIAZID reports
4
Deaths
60
Hospitalizations
How Dangerous Is Neutropenia From ISONIAZID?
Of the 101 reports, 4 (4.0%) resulted in death, 60 (59.4%) required hospitalization, and 3 (3.0%) were considered life-threatening.
Is Neutropenia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for ISONIAZID. However, 101 reports have been filed with the FAERS database.
What Other Side Effects Does ISONIAZID Cause?
Drug-induced liver injury (766)
Drug ineffective (607)
Drug reaction with eosinophilia and systemic symptoms (550)
Pyrexia (517)
Nausea (488)
Paradoxical drug reaction (433)
Off label use (406)
Drug resistance (367)
Hepatotoxicity (349)
Headache (324)
What Other Drugs Cause Neutropenia?
CLOZAPINE (18,981)
CYCLOPHOSPHAMIDE (7,352)
LENALIDOMIDE (6,909)
RITUXIMAB (6,607)
PALBOCICLIB (6,423)
DEXAMETHASONE (6,050)
DOXORUBICIN (5,891)
CARBOPLATIN (5,314)
VINCRISTINE (4,982)
PACLITAXEL (4,553)
Which ISONIAZID Alternatives Have Lower Neutropenia Risk?
ISONIAZID vs ISONIAZID\PYRAZINAMIDE\RIFAMPIN
ISONIAZID vs ISONIAZID\PYRIDOXINE\SULFAMETHOXAZOLE\TRIMETHOPRIM
ISONIAZID vs ISONIAZID\RIFAMPIN
ISONIAZID vs ISOPROPANOLAMINE
ISONIAZID vs ISOPROPYL ALCOHOL