ISONIAZID\PYRAZINAMIDE\RIFAMPIN for Tuberculosis: Side Effects & Safety Data
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There are 196 adverse event reports in the FDA FAERS database where ISONIAZID\PYRAZINAMIDE\RIFAMPIN was used for Tuberculosis.
Most Reported Side Effects for ISONIAZID\PYRAZINAMIDE\RIFAMPIN
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Hepatic cytolysis | 50 | 12.1% | 5 | 31 |
| Drug reaction with eosinophilia and systemic symptoms | 39 | 9.5% | 9 | 27 |
| Hepatocellular injury | 37 | 9.0% | 4 | 24 |
| Cholestasis | 32 | 7.8% | 10 | 16 |
| Thrombocytopenia | 20 | 4.9% | 3 | 18 |
| Rash maculo-papular | 19 | 4.6% | 2 | 14 |
| Rash | 17 | 4.1% | 9 | 7 |
| Pyrexia | 16 | 3.9% | 2 | 12 |
| Jaundice | 15 | 3.6% | 2 | 14 |
| Pruritus | 15 | 3.6% | 0 | 14 |
| Mixed liver injury | 14 | 3.4% | 1 | 14 |
| Vomiting | 13 | 3.2% | 1 | 11 |
| Condition aggravated | 12 | 2.9% | 0 | 7 |
| Eosinophilia | 12 | 2.9% | 2 | 9 |
| Hepatic failure | 12 | 2.9% | 4 | 11 |
Other Indications for ISONIAZID\PYRAZINAMIDE\RIFAMPIN
Pulmonary tuberculosis (78)
Lymph node tuberculosis (26)
Disseminated tuberculosis (20)
Product used for unknown indication (13)
Bone tuberculosis (10)
Meningitis tuberculous (7)
Peritoneal tuberculosis (7)
Pulmonary tuberculoma (5)
Other Drugs Used for Tuberculosis
LINEZOLID (2,881)
PYRAZINAMIDE (2,687)
ISONIAZID (2,576)
BEDAQUILINE (2,546)
RIFAMPIN (2,323)
ETHAMBUTOL (2,213)
CLOFAZIMINE (2,006)
LEVOFLOXACIN (1,310)
MOXIFLOXACIN (1,129)
DELAMANID (1,101)