JAKAFI for Splenomegaly: Side Effects & Safety Data
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There are 29 adverse event reports in the FDA FAERS database where JAKAFI was used for Splenomegaly.
Most Reported Side Effects for JAKAFI
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Platelet count decreased | 165 | 9.4% | 9 | 28 |
| Fatigue | 162 | 9.3% | 6 | 12 |
| Haemoglobin decreased | 150 | 8.6% | 6 | 19 |
| Anaemia | 145 | 8.3% | 5 | 23 |
| Dizziness | 106 | 6.1% | 1 | 5 |
| Diarrhoea | 105 | 6.0% | 4 | 5 |
| Headache | 102 | 5.8% | 1 | 4 |
| Death | 92 | 5.3% | 92 | 23 |
| Asthenia | 74 | 4.2% | 5 | 14 |
| Nausea | 72 | 4.1% | 1 | 5 |
| Weight increased | 70 | 4.0% | 0 | 4 |
| Blood count abnormal | 63 | 3.6% | 1 | 10 |
| Contusion | 61 | 3.5% | 2 | 1 |
| Dyspnoea | 58 | 3.3% | 3 | 8 |
| Drug dose omission | 54 | 3.1% | 2 | 8 |
Other Indications for JAKAFI
Myelofibrosis (1,314)
Polycythaemia vera (81)
Myelodysplastic syndrome (31)
Myeloproliferative disorder (29)
Essential thrombocythaemia (18)
Blood disorder (12)
Leukaemia (8)
Polycythaemia (8)
Myeloid metaplasia (6)
Other Drugs Used for Splenomegaly
RUXOLITINIB (270)
RITUXIMAB (27)
FEDRATINIB (11)
BENDAMUSTINE (8)
IBRUTINIB (8)
PREDNISOLONE (6)
HYDROXYUREA (5)
PREDNISONE (5)