JAKAFI for Myelofibrosis: Side Effects & Safety Data
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There are 1,314 adverse event reports in the FDA FAERS database where JAKAFI was used for Myelofibrosis.
Most Reported Side Effects for JAKAFI
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Platelet count decreased | 165 | 9.4% | 9 | 28 |
| Fatigue | 162 | 9.3% | 6 | 12 |
| Haemoglobin decreased | 150 | 8.6% | 6 | 19 |
| Anaemia | 145 | 8.3% | 5 | 23 |
| Dizziness | 106 | 6.1% | 1 | 5 |
| Diarrhoea | 105 | 6.0% | 4 | 5 |
| Headache | 102 | 5.8% | 1 | 4 |
| Death | 92 | 5.3% | 92 | 23 |
| Asthenia | 74 | 4.2% | 5 | 14 |
| Nausea | 72 | 4.1% | 1 | 5 |
| Weight increased | 70 | 4.0% | 0 | 4 |
| Blood count abnormal | 63 | 3.6% | 1 | 10 |
| Contusion | 61 | 3.5% | 2 | 1 |
| Dyspnoea | 58 | 3.3% | 3 | 8 |
| Drug dose omission | 54 | 3.1% | 2 | 8 |
Other Indications for JAKAFI
Polycythaemia vera (81)
Myelodysplastic syndrome (31)
Myeloproliferative disorder (29)
Splenomegaly (29)
Essential thrombocythaemia (18)
Blood disorder (12)
Leukaemia (8)
Polycythaemia (8)
Myeloid metaplasia (6)
Other Drugs Used for Myelofibrosis
RUXOLITINIB (21,650)
PACRITINIB (1,586)
FEDRATINIB (682)
MOMELOTINIB (526)
LENALIDOMIDE (496)
THALIDOMIDE (349)
DEFERASIROX (150)
HYDROXYUREA (129)
JAKAVI (98)
AZACITIDINE (94)