PACRITINIB for Myelofibrosis: Side Effects & Safety Data
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There are 1,586 adverse event reports in the FDA FAERS database where PACRITINIB was used for Myelofibrosis.
Most Reported Side Effects for PACRITINIB
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Diarrhoea | 536 | 20.9% | 13 | 64 |
| Off label use | 459 | 17.9% | 33 | 56 |
| Fatigue | 320 | 12.5% | 9 | 40 |
| Product dose omission issue | 279 | 10.9% | 6 | 60 |
| Death | 261 | 10.2% | 260 | 23 |
| Nausea | 246 | 9.6% | 8 | 36 |
| Platelet count decreased | 237 | 9.3% | 4 | 42 |
| Haemoglobin decreased | 171 | 6.7% | 5 | 43 |
| Asthenia | 119 | 4.6% | 5 | 22 |
| Drug ineffective | 98 | 3.8% | 2 | 9 |
| Dizziness | 96 | 3.8% | 4 | 12 |
| Splenomegaly | 84 | 3.3% | 2 | 11 |
| Transfusion | 83 | 3.2% | 1 | 23 |
| Constipation | 75 | 2.9% | 2 | 9 |
| Dyspnoea | 75 | 2.9% | 3 | 23 |
Other Indications for PACRITINIB
Myeloproliferative neoplasm (365)
Product used for unknown indication (154)
Myelodysplastic syndrome (112)
Polycythaemia vera (112)
Essential thrombocythaemia (66)
Acute myeloid leukaemia (21)
Thrombocytopenia (21)
Marrow hyperplasia (17)
Chronic myelomonocytic leukaemia (13)
Immune thrombocytopenia (12)
Other Drugs Used for Myelofibrosis
RUXOLITINIB (21,650)
JAKAFI (1,314)
FEDRATINIB (682)
MOMELOTINIB (526)
LENALIDOMIDE (496)
THALIDOMIDE (349)
DEFERASIROX (150)
HYDROXYUREA (129)
JAKAVI (98)
AZACITIDINE (94)