FEDRATINIB for Myelofibrosis: Side Effects & Safety Data
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There are 682 adverse event reports in the FDA FAERS database where FEDRATINIB was used for Myelofibrosis.
Most Reported Side Effects for FEDRATINIB
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Diarrhoea | 143 | 10.2% | 13 | 28 |
| Death | 138 | 9.8% | 138 | 3 |
| Nausea | 114 | 8.1% | 0 | 13 |
| Fatigue | 105 | 7.5% | 0 | 10 |
| Vomiting | 74 | 5.3% | 10 | 20 |
| Constipation | 59 | 4.2% | 9 | 18 |
| Platelet count decreased | 48 | 3.4% | 0 | 10 |
| Asthenia | 47 | 3.4% | 2 | 14 |
| Haemoglobin decreased | 46 | 3.3% | 1 | 12 |
| Full blood count decreased | 45 | 3.2% | 0 | 14 |
| Drug ineffective | 42 | 3.0% | 0 | 1 |
| Anaemia | 41 | 2.9% | 1 | 11 |
| Off label use | 40 | 2.9% | 7 | 6 |
| Dizziness | 37 | 2.6% | 0 | 8 |
| Illness | 34 | 2.4% | 1 | 6 |
Other Indications for FEDRATINIB
Product used for unknown indication (307)
Myeloproliferative neoplasm (146)
Primary myelofibrosis (77)
Polycythaemia vera (69)
Off label use (56)
Essential thrombocythaemia (28)
Myelodysplastic syndrome (27)
Splenomegaly (11)
Hairy cell leukaemia (9)
Thrombocytosis (8)
Other Drugs Used for Myelofibrosis
RUXOLITINIB (21,650)
PACRITINIB (1,586)
JAKAFI (1,314)
MOMELOTINIB (526)
LENALIDOMIDE (496)
THALIDOMIDE (349)
DEFERASIROX (150)
HYDROXYUREA (129)
JAKAVI (98)
AZACITIDINE (94)